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GenomicsGenome-wide DNA-binding profile of HNF4A and genome occupancy of the histone modifications H3K4me1, H3K27ac in kidneys from Bicc1 WT and KO mice by ChIPseq.
Mutations in Bicaudaul C 1 (BICC1), evolutionary conserved RNA-binding protein, cause renal cysts in mice and humans. These renal cysts are reminiscent of Polycystic Kidney Disease (PKD). How BICC1 is involved in the pathogenesis of polycystic kidney disease is still unknown. Recent studies highligh...
ORGANISM(S): Mus musculus 
2020-01-20 | E-MTAB-6424 | biostudies-arrayexpress
TranscriptomicsRenal transcriptome profiling by RNAseq in Bicc1 WT and KO mice.
Mutations in Bicaudaul C 1 (BICC1), evolutionary conserved RNA-binding protein, cause renal cysts in mice and humans. These renal cysts are reminiscent of Polycystic Kidney Disease (PKD). How BICC1 is involved in the pathogenesis of polycystic kidney disease is still unknown. Recent studies highligh...
ORGANISM(S): Mus musculus 
2020-01-20 | E-MTAB-6423 | biostudies-arrayexpress
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