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TranscriptomicsColon biopsies from Crohns patients and healthy controls
The aim of this study was to investigate differential intestinal gene expression in patients with Crohn's disease (CD) and controls. 172 biopsies from CD and control subjects were studied. Endoscopic biopsies were taken at ileocolonoscopy from five specific anatomical locations including the termi...
ORGANISM(S): Homo sapiens 
2010-07-19 | E-GEOD-20881 | biostudies-arrayexpress
TranscriptomicsColon biopsies from UC patients and healthy controls
Transcriptional profiling of colon epithelial biopsies from ulcerative colitis patients and healthy control donors. Study aims to survey and analyze variation from disease in different GI regions. Keywords: disease state analysis Biopsies from a variety of anatomic locations, from patients of variou...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-11223 | biostudies-arrayexpress
TranscriptomicsThe alarmin IL-33 amplifies an immune response in the degenerating retina
ST2 heterodimerizes with IL-1RAcp to form the receptor for IL-33, which is primarily associated with allergic inflammation by inducing Th2 responses. Recently, however, IL-33 was found to be expressed in the central nervous system and in retinal Muller cells which imply functions, as yet undescribed...
ORGANISM(S): Mus musculus 
2015-12-17 | E-GEOD-74695 | biostudies-arrayexpress
TranscriptomicsGene expression of baseline biopsies from etrolizumab-treated ulcerative colitis (UC) patients
RNA sequencing was performed on RNA isolated from baseline biopsies from UC patients enrolled in the Phase II EUCALYPTUS study of etrolizumab. Gene expression differences were identified in a subset of anti-TNF naïve patients that achieved clinical remission at 10 weeks in response to etrolizumab. ...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-72819 | biostudies-arrayexpress
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