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UnknownCharacterizing alternative splicing effects on protein interaction networks with LINDA.
Not available
S-EPMC10311343 | biostudies-literature
ProteomicsEnhancing the cardiac pig transcriptome by long-read sequencing and in-depth proteomics
Clinically translatable large animal models have become indispensable for cardiovascular research, clinically relevant proof of concept studies and for novel diagnostic and therapeutic interventions. In particular, the pig as emerged as an essential cardiovascular disease model, because its heart, c...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-10-29 | PXD018985 | Pride
Pig Tmt Annotation Proteomics Transcriptomics Cardiac Nanopore Lcms 
TranscriptomicsC. elegans: Dauers and Dauer-Exit at 12 hour time-point vs. Mix-stage worms
Transcriptional profiling of C. elegans worms from (1) dauer stage, or (2) dauer-exit at 12 hours stage, compared to mix-stage worms as a common reference. The goal was to determine genes regulated during dauer development and recovery or exit from dauer stage. This data was then compared to data g...
ORGANISM(S): Caenorhabditis elegans 
2011-07-27 | E-GEOD-30977 | biostudies-arrayexpress
TranscriptomicsmicroRNAs in C. elegans, P. pacificus, and S. ratti: Conserved miRNAs are candidate post-transcriptional regulators of developmental arrest in free-living and parasitic nematodes
Animal development is complex yet surprisingly robust. Animals may develop alternative phenotypes conditional on environmental changes. Under unfavorable conditions C. elegans larvae enter the dauer stage, a developmentally arrested, long-lived, and stress-resistant state. Dauer larvae of free-livin...
ORGANISM(S): Pristionchus pacificus 
2013-07-04 | E-GEOD-41402 | biostudies-arrayexpress
TranscriptomicsAnalysis of intron sequences reveals hallmarks of circular RNA biogenesis in animals
Circular RNAs (circRNAs) are a large class of animal RNAs. To investigate possible circRNA functions, it is important to understand circRNA biogenesis. Besides human Alu repeats, sequence features that promote exon circularization are largely unknown. We experimentally identified new circRNAs in C. ...
ORGANISM(S): Caenorhabditis elegans 
2015-01-06 | E-GEOD-63823 | biostudies-arrayexpress
TranscriptomicsPristionchus pacificus and Caenorhabditis elegans: Dauer and Dauer exit versus mix-stage comparisons
This SuperSeries is composed of the following subset Series: GSE30977: C. elegans: Dauers and Dauer-Exit at 12 hour time-point vs. Mix-stage worms GSE31861: P. pacificus : Dauers and Dauer-Exit at 12 hour time-point vs. Mix-stage worms Refer to individual Series
ORGANISM(S): Caenorhabditis elegans 
2012-03-22 | E-GEOD-36644 | biostudies-arrayexpress
TranscriptomicsP. pacificus : Dauers and Dauer-Exit at 12 hour time-point vs. Mix-stage worms
Transcriptional profiling of P. pacificus worms from (1) dauer stage, or (2) dauer-exit at 12 hours stage, compared to mix-stage worms as a common reference. The goal was to determine genes regulated during dauer development and recovery or exit from dauer stage. This data was then compared to data ...
ORGANISM(S): Pristionchus pacificus 
2011-09-02 | E-GEOD-31861 | biostudies-arrayexpress
TranscriptomicsWT and Mk2/3 KO MEFs response to etoposide
Primary mouse embryonic fibroblasts (MEFs) from wt and MK2/3 KO mice were treated with 20µM etoposide. Primary MEFs from wt and MK2/3 KO mice were treated with 20µM etoposide and RNA extracted after 1h and 6h.
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-67266 | biostudies-arrayexpress
TranscriptomicsMML-1/Mondo complexes regulate HLH-30/TFEB via TOR inhibition to promote longevity in response to signals from the reproductive system
Comprehensive transcriptome analysis of hlh-30, mml-1 and mxl-2 in N2 (wildtype) and glp-1 background.
ORGANISM(S): Caenorhabditis elegans 
2016-03-21 | E-MTAB-3686 | biostudies-arrayexpress
TranscriptomicsHeart RNA-Seq of cardiomyocyte-specific and inducible Prmt5 knockout mouse model, AVV9-ACADVL rescue
Our study introduces a novel animal model featuring a cardiomyocyte-specific, inducible knockout of the Prmt5. The primary aim of this model is to investigate the regulatory mechanisms of PRMT5, the main representative of type II PRMTs. We found that PRMT5 controls Acadvl mRNA splicing, and that dis...
ORGANISM(S): Mus musculus 
2026-05-15 | E-MTAB-14396 | biostudies-arrayexpress
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