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MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
GenomicsHomo sapiens
Effects of Genistein on LNCaP Gene Expression
PRJNA132285 | ENA
UnknownNext-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection.
Not available
S-EPMC3257944 | biostudies-literature
TranscriptomicsThe role of microRNA miR-17-92 in MYC oncogene addiction
miR-17-92 mediates the MYC oncogene addiction in a conditional mouse lymphoma model. To identify targets of miR-17-92 in this model, miR-17-92 was expressed in the conditional lymphoma cell lines using MSCV-puro. Both control and miR-17-92-expressing conditional lymphoma cell lines were treated wit...
ORGANISM(S): Mus musculus 
2014-05-29 | E-GEOD-57507 | biostudies-arrayexpress
ProteomicsTumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis
Development of effective therapies against brain metastasis is currently hindered by limitations in our understanding of the molecular mechanisms driving it. Here we define the contributions of tumour-secreted exosomes to brain metastatic colonization and demonstrate that pre-conditioning the brain ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD015210 | Pride
Tumour exosomal cemi brain metastasis 
TranscriptomicsGene expression profiling of Notch1 knockout mouse liver samples and murine hepatic angiosarcoma cell lines.
This work is part of the paper: Generation of a murine hepatic angiosarcoma cell line and reproducible mouse tumor model, Rothweiler S et al, Laboratory Investigation, 2014 (accepted) Hepatic Angiosarcoma (AS) is a rare and highly aggressive tumor of endothelial origin with dismal prognosis. Studies...
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-57655 | biostudies-arrayexpress
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