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UnknownSynthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein.
Not available
S-EPMC8434109 | biostudies-literature
TranscriptomicsOncogenic CARMA1 couples NF-κB and β-Catenin signaling in diffuse large B cell lymphomas
Constitutive activation of the anti-apoptotic NF-κB signaling pathway is a hallmark of the activated B-cell-like (ABC) subtype of diffuse large B-cell lymphomas (DLBCL) that is characterized by adverse survival. Recurrent oncogenic mutations are found in the scaffold protein CARMA1 (CARD11) that co...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-70025 | biostudies-arrayexpress
ProteomicsMurine hippocampal phosphoproteome LC-MSMS
The hippocampus plays an important role in spatial memory and the conversion of short-term to long-term memory. Several studies have reported the presence of a peripheral oscillator in the hippocampus, and have highlighted the importance of circadian regulation in memory formation. In this study we ...
ORGANISM(S): Mus musculus (Mouse) 
2017-04-11 | PXD005669 | Pride
Circadian Hippocampus Phosphoproteome Mouse 
GenomicsCircadian cycling of genome-wide histone methylation
Daily (circadian) clocks are essential for regulating and coordinating physiology in mammals. Modulation of local chromatin structure has been shown for only a small number of genes, principally thought to be directly modulated by Clock-mediated histone acetylation. Here we show that genome-wide cha...
ORGANISM(S): Mus musculus 
2013-01-08 | E-GEOD-23550 | biostudies-arrayexpress
TranscriptomicsRNAseq analysis of SCLC PDX models
We investigated the gene expression changes in a library of small cell lung carcinoma (SCLC) patient-derived xenograft (PDX) models.
ORGANISM(S): Homo sapiens 
2022-02-07 | E-MTAB-11230 | biostudies-arrayexpress
TranscriptomicsRNAseq analysis of meso PDX models
We investigated the gene expression changes in a library of meso PDX models.
ORGANISM(S): Homo sapiens 
2022-06-17 | E-MTAB-11783 | biostudies-arrayexpress
TranscriptomicsAnalysis of the coding exome of follicular lymphoma
Follicular lymphoma (FL) constitutes the second most common non-Hodgkin lymphoma in the Western world. FL carries characteristic recurrent structural genomic aberrations. However, information regarding the coding genome in FL is still evolving. Here, we describe the results of massively parallel ex...
ORGANISM(S): Homo sapiens 
2014-01-17 | E-GEOD-50973 | biostudies-arrayexpress
UnknownEffect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study.
Not available
S-EPMC11056389 | biostudies-literature
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