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TranscriptomicsControl of neural specification programmes by the NuRD complex
Apical progenitors from wild type and NestinCre:Mbd3Flox/Flox embryos at E12.5, E14.5 and E16.5 were used for gene expression microarray analyses to identify gene expression changes dependent upon a functional NuRD complex.
ORGANISM(S): Mus musculus 
2015-12-12 | E-MTAB-1332 | biostudies-arrayexpress
TranscriptomicsCHiCAGO: Robust Detection of DNA Looping Interactions in Capture Hi-C data
Capture Hi-C (CHi-C) is a state-of-the art method for profiling chromosomal interactions involving targeted regions of interest (such as gene promoters) globally and at high resolution. Signal detection in CHi-C data involves a number of statistical challenges that are not observed when using other ...
ORGANISM(S): Mus musculus 
2016-05-18 | E-GEOD-81503 | biostudies-arrayexpress
GenomicsPromoter capture mESC and fetal liver
Genome organization influences transcriptional regulation by facilitating interactions between gene promoters and distal regulatory elements. To analyse distal promoter contacts we used Capture Hi-C (CHi-C) to enrich for promoter-interactions in HiC libraries from mouse ESC and E14.5 fetal liver. Pl...
ORGANISM(S): Mus musculus 
2015-02-01 | E-MTAB-2414 | biostudies-arrayexpress
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