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GenomicsGlobal DNA Hypermethylation in Down Syndrome Placenta [Bisulfite-Seq]
We have performed genome-wide DNA methylation analysis at single base resolution and gene expression analysis, resulted in hypermethylation in all autosomes in DS samples, mediated by down-regulation of all three TET family genes, and down-regulation of REST/NRSF. Genes located on chr21 were up-regu...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-42074 | biostudies-arrayexpress
TranscriptomicsGlobal DNA Hypermethylation in Down Syndrome Placenta
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-42144 | biostudies-arrayexpress
TranscriptomicsGlobal DNA Hypermethylation in Down Syndrome Placenta [RNA-Seq]
We have performed genome-wide DNA methylation analysis at single base resolution and gene expression analysis, resulted in hypermethylation in all autosomes in DS samples, mediated by down-regulation of all three TET family genes, and down-regulation of REST/NRSF. Genes located on chr21 were up-regu...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-42142 | biostudies-arrayexpress
TranscriptomicsAllele-specific Methylation of Human Placental Tissue
In this study, we screened human placental samples for allele-specific methylation and subsequently novel imprinted genes associated with these regions. We used reduced representation bisulfite sequencing to identify partially methylated CpG islands (CGIs) in the human placental genome. We were able...
ORGANISM(S): Homo sapiens 
2013-10-09 | E-GEOD-40955 | biostudies-arrayexpress
TranscriptomicsOryza sativa japonica Transcriptome or Gene expression
In this study, we examined the transcriptome dynamics within the matured fully expanded rice leaf and used strand-specific RNA sequencing to generate a comprehensive transcriptome dataset for the mature rice leaf. The rice Nipponbare (Oryza sativa l. japonica) seedlings were grown in the greenhouse....
ORGANISM(S): Oryza sativa Japonica Group 
2015-08-16 | E-MTAB-4372 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles of Pregnant and Non-pregnant Whole Blood
Comparison of gene expression profiles in whole blood collected from pregnant and non-pregnant females. Peripheral whole blood samples from 5 third trimester pregnant females and 5 non-pregnant females were collected. The gene expression profiles of the two groups were compared using Affymetrix HG-U...
ORGANISM(S): Homo sapiens 
2009-06-10 | E-GEOD-14771 | biostudies-arrayexpress
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