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ProteomicsCharacterization of the acetylome associated with rapamycin-induced autophagy in HeLa cells
Autophagy is a lysosomal-mediated catabolic process that degrades cytoplasmic components to help maintain cellular homeostasis and cell survival during exposure to stress. Lysine acetylation is a reversible post-translational modification that plays an important role in the regulation of diverse cel...
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD005793 | Pride
Autophagy  rapamycin  acetylome  acetylation  acetyltransferase 
ProteomicsPhosphoproteome analysis reveals the importance of Greatwall-endosulfine pathway to regulate cell-cycle progression upon the rapamycin-induced autophagy
Protein phosphorylation plays an important role in the process of autophagy. Autophagy is associated with cell cycle, which is controlled by the balance between the cyclin-dependent kinases and phosphatases activities. However, up to now, the signal transduction pathways that underlied rapamycin-ind...
ORGANISM(S): Homo sapiens (Human) 
2021-04-06 | PXD014737 | Pride
Autophagy  phosphoproteome  rapamycin  cell cycle  cdk1 
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