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TranscriptomicsKDM4A regulated genes in human squamous carcinoma cells
To establish a robust cellular model system for screening genes associated with cell invasion, we over-expressed the oncogenic translocated promoter region (Tpr)-MET proteins in SCC23 cells (SCC23/MET). Using a functional siRNA screen, we identified that the histone demethylase KDM4A played a critic...
ORGANISM(S): Homo sapiens 
2013-05-03 | E-GEOD-44238 | biostudies-arrayexpress
TranscriptomicsGenes regulated by miR-203 in breast cancer cell line MDA-MB-231
To investigate the mechanism through which miR-203 inhibited the breast cancer cell invasion, we overpression miR-203 in MDA-MB-231 cell line and performed a microarray to examine the genes which maybe targeted and down-regulated by miR-203. We made a stable cell line(MB231/miR-203) which overexpres...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-44239 | biostudies-arrayexpress
ProteomicsUltradeep N-glycoproteome Atlas of Mouse Reveals Spatiotemporal Signatures of Brain Aging and Neurodegenerative Diseases
The current depth of site-specific N-glycoproteomics is insufficient to fully characterize glycosylation events in biological samples. Herein, we achieved an ultradeep and precision analysis of the N-glycoproteome of mouse tissues by integrating multiple workflows. The largest N-glycoproteomic datas...
ORGANISM(S): Mus Musculus 
2025-03-04 | PXD061436 |
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