Microarray analysis was carried out on human monocytes (Mono) and monocyte-derived macrophages (MDM) (n = 4 donors) that were subjected to normoxic (N) or hypoxic (H) conditions. Purified human monocytes and their MDM were cultured for 24 h in CSF-1 (5000U/ml) under normoxic or hypoxic conditions.
In this study, we compared BMM and GM-BMM from wild-type and IFNAR1-/- mice, which lack the ability to respond to endogenous type I IFN. A comparison of the two macrophage is made using microarray profiling
