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TranscriptomicsTransformation of the Fallopian Tube Secretory Epithelium Leads to High-grade Serous Ovarian Cancer in BRCA/P53/PTEN Models
Our study presents the first genetic models of de novo high-grade serous carcinomas (HGSC) that originate in fallopian tube secretory epithelial cells and recapitulate the key genetic alterations and precursor lesions characteristic of human invasive ovarian cancer. Genomic copy number analysis, us...
ORGANISM(S): Mus musculus 
2013-12-17 | E-GEOD-49827 | biostudies-arrayexpress
ProteomicsEpithelial ovarian cancer biomarker
Protein biomarkers of early stages of disease are critical for managing the disease and improving outcomes. Unfortunately, discovery of protein biomarkers is hampered by the limited availability of assays for sensitive and reproducible quantification of proteins in complex biological matrices such a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-02 | MSV000084048 | MassIVE
ProteomicsA targeted strategy for developing proteomic biomarkers: a case study of epithelial ovarian cancer
Protein biomarkers for epithelial ovarian cancer are critical for the early detection of the cancer to improve patient prognosis and for the clinical management of the disease to monitor treatment response and to detect recurrences. Unfortunately, the discovery of protein biomarkers is hampered by t...
ORGANISM(S): Homo Sapiens 
2019-08-14 | PXD014474 | panorama
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