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GenomicsOverexpression of Let-7a Mitigates Diploidization in Mouse Androgenetic Haploid Embryonic Stem Cells
Overexpression of Let-7a Mitigates Diploidization in Mouse Androgenetic Haploid Embryonic Stem Cells
PRJNA1057860 | ENA
GenomicsOverexpression of Let-7a Mitigates Diploidization in Mouse Androgenetic Haploid Embryonic Stem Cells
Mouse androgenetic haploid embryonic stem cells (mAG-haESCs) can be utilized to uncover gene functions, especially those of genes with recessive effects, and to produce semicloned mice when injected into mature oocytes. However, mouse haploid cells undergo rapid diploidization during long-term cultu...
ORGANISM(S): Mus musculus 
2024-01-30 | GSE252136 | GEO
GenomicsInhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during the Differentiation
Inhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during the Differentiation
PRJNA623293 | ENA
UnknownIncipient diploidization of the medicinal plant Perilla within 10,000 years.
Not available
S-EPMC8448860 | biostudies-literature
UnknownPhenotypic diploidization in plant functional traits uncovered by synthetic neopolyploids in Dianthus broteri.
Not available
S-EPMC8760854 | biostudies-literature
TranscriptomicsInhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during the Differentiation
Phenotypes of haploid embryonic stem cells (haESCs) are dominant for recessive traits in mice. However, one major obstacle to their use is self-diploidization in daily culture. Although haESCs maintain haploidy well by deleting p53, whether they can sustain haploidy in differentiated status and the ...
ORGANISM(S): Mus musculus 
2020-04-07 | GSE148118 | GEO
UnknownInhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during Differentiation.
Not available
S-EPMC7363743 | biostudies-literature
UnknownThe role of gene dosage in budding yeast centrosome scaling and spontaneous diploidization.
Not available
S-EPMC7775121 | biostudies-literature
UnknownGenomic insights into genetic diploidization in the homosporous fern Adiantum nelumboides.
Not available
S-EPMC9387920 | biostudies-literature
UnknownSelf-diploidization of human haploid parthenogenetic embryos through the Rho pathway regulates endomitosis and failed cytokinesis.
Not available
S-EPMC5484709 | biostudies-literature
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