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MetabolomicsArginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease
Amino acid metabolism provides significant insight into the development and prevention of many viral diseases. Therefore, the present study aimed to compare the amino acid profiles of hand, foot, and mouth disease (HFMD) patients with those of healthy individuals and to further reveal the molecular ...
2024-10-25 | MTBLS11341 | MetaboLights
MetabolomicsNon-targeted metabolomics analysis of the effect of strain MR-86 on the rhizosphere soil metabolome of Saposhnikovia divaricata under different disease severity levels
To clarify the effect of strain MR-86 on the rhizosphere soil metabolome of S. divaricata under different disease severity levels, a non-targeted metabolomics approach was applied to analyze soil samples from the GFQ, GFZ, and MR-86etGFQ treatments.
2026-04-16 | MTBLS14298 | MetaboLights
MetabolomicsQuantitative LC-MS study of compounds found predictive of COVID-19 severity and outcome

INTRODUCTION: Since the beginning of the SARS-CoV-2 pandemic in December 2019 multiple metabolomics studies have proposed predictive biomarkers of infection severity and outcome. Whilst some trends have emerged, the findings remain intangible and uninformative when it comes to n...

2024-04-23 | MTBLS7429 | MetaboLights
MetabolomicsSerum metabolomics profiling identifies new predictive biomarkers for disease severity in COVID-19 patients
Not available
ORGANISM(S): Homo sapiens 
ST002301 | MetabolomicsWorkbench
MetabolomicsBiomarker Discovery in Oral Cancer (OSMF & OSCC) and its severity

Oral squamous cell carcinoma (OSCC) is frequently the outcome of oral submucous fibrosis (OSMF), a common possibly premalignant disease. In our study, a cohort of 50 patients with OSCC and OSMF, along with 50 healthy controls, was analyzed to identify significant metabolic differences between the...

2024-10-23 | MTBLS11009 | MetaboLights
MetabolomicsRole of environmental toxicants in modulating disease severity in children with NAFLD
Not available
ORGANISM(S): Homo sapiens 
ST001428 | MetabolomicsWorkbench
MetabolomicsMulti-0mics and Machine Learning-Based Profiling of Severity signatures in Mycoplasma Pneumoniae Infection in children

Mycoplasma pneumoniae pneumonia (MPP) is a common respiratory infection in children. Yet the mechanisms driving its progression to severe disease remain poorly understood. This study employs a comprehensive proteomic and metabolomic approach to elucidate severity-related pathways and identify pot...

2026-01-04 | MTBLS13511 | MetaboLights
MetabolomicsValidation: Multi-Omics and Machine Learning-Based Profiling of Severity Signatures in Mycoplasma Pneumoniae Infection in Children

Mycoplasma pneumoniae pneumonia (MPP) is a common respiratory infection in children, yet the mechanisms driving its progression to severe disease remain poorly understood. This study employs a comprehensive proteomic and metabolomic approach to elucidate severity-related pathways and identify pot...

2026-01-05 | MTBLS13504 | MetaboLights
MetabolomicsMetabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation
Not available
ORGANISM(S): Homo sapiens 
ST002194 | MetabolomicsWorkbench
MetabolomicsLongitudinal Metabolomics of Human Plasma Reveals Robust Prognostic Markers of COVID-19 Disease Severity (part I)
Not available
ORGANISM(S): Homo sapiens 
ST001849 | MetabolomicsWorkbench
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