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TranscriptomicsRibosome profiling study of dom34 and hbs1 knockout strains using short (16-nt) and long (28-nt) monosome-protected footprints and disome-protected footprints
Ribosomes that stall before completing peptide synthesis must be recycled and returned to the cytoplasmic pool. The protein Dom34 and cofactors Hbs1 and Rli1 can dissociate stalled ribosomes in vitro, but the identity of targets in the cell is unknown. Here we use ribosome profiling methodology to r...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-19 | E-GEOD-52968 | biostudies-arrayexpress
ProteomicsDisome-seq reveals sequence-mediated coupling of translational pauses and protein structures
The regulation of translation elongation plays a vital role in protein folding; an adequate translational pause provides time and cellular environments for the co-translational folding of nascent peptides. However, the genomic landscape, sequence determinants, and molecular consequences of translati...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-12-10 | PXD015271 | Pride
Silac Saccharomyces cerevisiae 
GenomicsDisome profiling of rocaglamide A treatment in HEK293FT cells
Disome profiling of rocaglamide A treatment in HEK293FT cells
PRJNA831100 | ENA
GenomicsDisome and trisome profiling reveal targets of ribosome quality control
Disome and trisome profiling reveal targets of ribosome quality control
PRJNA578122 | ENA
UnknownDisome and Trisome Profiling Reveal Genome-wide Targets of Ribosome Quality Control.
Not available
S-EPMC7484464 | biostudies-literature
UnknownProtocol for Disome Profiling to Survey Ribosome Collision in Humans and Zebrafish.
Not available
S-EPMC7757362 | biostudies-literature
TranscriptomicsMonosome and disome profiling of Flag-STAU1 Flp-In 293 T-REx cells
Monosome and disome profiling was performed on Flag-STAU1 Flp-In 293 T-REx to study the causes of ribosomal collisions, and whether this may be modulated by the presence/absence of Staufen-1. Cells were treated with either an siRNA targeting STAU1 transcript (4x samples) or a control siRNA (2x sam...
ORGANISM(S): Homo sapiens 
2023-04-30 | E-MTAB-9669 | biostudies-arrayexpress
GenomicsMonosome and disome profiling of Flag-STAU1 Flp-In 293 T-REx cells
Monosome and disome profiling of Flag-STAU1 Flp-In 293 T-REx cells
PRJEB40792 | ENA
UnknownThe landscape of translational stall sites in bacteria revealed by monosome and disome profiling.
Not available
S-EPMC8848927 | biostudies-literature
TranscriptomicsDisome and trisome profiling reveal targets of ribosome quality control
The ribosome-associated protein quality control (RQC) system that resolves stalled translation events is activated when ribosomes collide and form disome, trisome or higher order complexes. However, it is unclear whether this system distinguishes collision complexes formed on defective mRNAs from th...
ORGANISM(S): Saccharomyces cerevisiae 
2020-05-26 | GSE139036 | GEO
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