Sort   by:  
 Page size 
TranscriptomicsExpression analysis in mouse female PGK12.1 ES cells by RNA-seq
Many animal species employ a chromosome-based mechanism of sex determination, which has led to coordinate evolution of dosage compensation systems. Dosage compensation not only corrects the imbalance in the number of X-chromosomes between the sexes, but is also hypothesized to correct dosage imbalan...
ORGANISM(S): Mus musculus 
2011-07-19 | E-GEOD-30690 | biostudies-arrayexpress
GenomicsDistribution of macroH2A1 nucleosomes in mouse liver chromatin
We produced a genome-wide map of the distribution of macroH2A1 histone variants in mouse liver chromatin using high-throughput sequencing of DNA from macroH2A1 nucleosomes. Although macroH2A1 nucleosomes are widely distributed across the genome, their local concentration varies over a range of 100-f...
ORGANISM(S): Mus musculus 
2010-11-10 | E-GEOD-18963 | biostudies-arrayexpress
TranscriptomicsExpression data from human triploid and diploid fibroblast cell cultures
Dosage compensation restores a balanced network of gene expression between autosomes and sex chromosomes in males (XY) and females (XX). In mammals, this is achieved by doubling the expression of X-linked genes in both sexes, together with X inactivation in females. X up-regulation may be controlled...
ORGANISM(S): Homo sapiens 
2009-11-06 | E-GEOD-18877 | biostudies-arrayexpress
Sort   by:  
 Page size