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MetabolomicsNPC1 regulates the distribution of phosphatidylinositol 4 kinases at Golgi and Lysosome membranes
Cholesterol and phosphoinositides (PI) are two critically important lipids that are found in cellular membranes and dysregulated in many disorders. Therefore, uncovering molecular pathways connecting these essential lipids may offer new therapeutic insights. We report that loss of function of lysoso...
2021-09-15 | MTBLS2612 | MetaboLights
GenomicsGlobal Reorganization of Chromatin Architecture during Embronic Stem Cell Differentiation
The 3D organization of the genome is important for regulation of diverse nuclear processes ranging from transcription to DNA replication. Knowledge of the higher order chromatin structure is critical for understanding mechanisms of gene regulation by long-range control elements such as enhancers and...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-52457 | biostudies-arrayexpress
UnknownStructural basis of Fic-mediated adenylylation.
Not available
S-EPMC2920259 | biostudies-literature
UnknownRnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension.
Not available
S-EPMC3627648 | biostudies-literature
UnknownA Single Kinase Generates the Majority of the Secreted Phosphoproteome.
Not available
S-EPMC4963185 | biostudies-literature
UnknownA Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity.
Not available
S-EPMC6424331 | biostudies-literature
UnknownPreexposure chemoprophylaxis for HIV prevention in men who have sex with men.
Not available
S-EPMC3079639 | biostudies-literature
Unknown20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years.
Not available
S-EPMC5734609 | biostudies-literature
UnknownCRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
Not available
S-EPMC10312804 | biostudies-literature
UnknownAdherence to adding inhaled corticosteroids to rescue therapy in a pragmatic trial with adults with asthma: A pilot study.
Not available
S-EPMC7188592 | biostudies-literature
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