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ProteomicsThe CGG triplet repeat binding protein 1 counteracts DNA secondary structure formation to prevent transcription-replication stress
Short tracts of trinucleotide repeats with less than 10 repeats are found frequently throughout the genome without any apparent negative impact on DNA replication fork progression or transcription elongation. CGG binding protein 1 (CGGBP1) binds to CGG triplet repeats and has been implicated in mult...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD045654 | Pride
Transcription-replication conflicts Genomic instability Cggbp1 R-loop structure Cgg-trinucleotide repeats Replication stress Transcription regulation Dna damag G-quadruplex structure 
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