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TranscriptomicsProfiling of adipose tissue from the F2 M16xICR mouse cross.
We profiled gene expression in adipose tissue from F2 progeny from a cross between the outbred M16 (selectively bred for rapid weight gain) and ICR (control) mouse strains. We developed a framework for reconstructing tissue-to-tissue coexpression networks between genes in hypothalamus, adipose or ad...
ORGANISM(S): Mus musculus 
2009-10-25 | E-GEOD-13746 | biostudies-arrayexpress
TranscriptomicsProfiling of hypothalamus tissue from the F2 M16xICR mouse cross.
We profiled gene expression in hypothalamus tissue from F2 progeny from a cross between the outbred M16 (selectively bred for rapid weight gain) and ICR (control) mouse strains. We developed a framework for reconstructing tissue-to-tissue coexpression networks between genes in hypothalamus, liver or...
ORGANISM(S): Mus musculus 
2010-06-22 | E-GEOD-13745 | biostudies-arrayexpress
TranscriptomicsProfiling of liver tissue from the F2 M16xICR mouse cross.
We profiled gene expression in liver tissue from F2 progeny from a cross between the outbred M16 (selectively bred for rapid weight gain) and ICR (control) mouse strains. We developed a framework for reconstructing tissue-to-tissue coexpression networks between genes in hypothalamus, liver or liver ...
ORGANISM(S): Mus musculus 
2009-10-25 | E-GEOD-13752 | biostudies-arrayexpress
TranscriptomicsRNAi profiling of mouse embryonic stem cells using short hairpin RNAs against Nanog, Oct4, Sox2, Esrrb, Tbx3, Tcl1, Mm.343880 and Dppa4
We present an integrated approach to identify genetic mechanisms that control self-renewal in mouse embryonic stem (ES) cells. Short hairpin RNA (shRNA) techniques are employed to down regulate a set of gene-products whose expression patterns suggest self-renewal regulatory functions. We focus on ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4679 | biostudies-arrayexpress
TranscriptomicsWhole blood gene expression from subjects with moderate to severe rheumatoid arthritis
Whole blood (paxgene) gene expression was measured using Affymetrix microarray from 377 individuals with rheumatoid arthritis. RA patient samples were collected from a phase III clinical trial of golimumab in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy (GO-FURTHER) accordi...
ORGANISM(S): Homo sapiens 
2016-03-16 | E-GEOD-74143 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (CR)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44768 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (PFC)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44770 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (VC)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44771 | biostudies-arrayexpress
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