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ProteomicsCaspase-8’s non-apoptotic role is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection.
Excessive inflammation and cytokine release are hallmarks of severe COVID-19. Programmed cell death is known to drive inflammation, however, its relevance in the pathogenesis of severe COVID-19 is unclear. Using a combination of gene-targeted murine models and transcriptomic approaches we found that...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-20 | PXD057656 | Pride
Sars-cov-2  caspase-8  inflammation  flip  covid-19  cytokines 
UnknownExternalized Keratin 8: A Target at the Interface of Microenvironment and Intracellular Signaling in Colorectal Cancer Cells.
Not available
S-EPMC6266717 | biostudies-literature
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