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GenomicsGenome-wide maps of RAP1 binding sites.
By performing chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq), we find that RAP1 binds to telomeres as well as to extra-telomeric sites through the (TTAGGG)2 consensus motif. Extra-telomeric RAP1 binding sites are particularly abundant at subtelomeric regions, ...
ORGANISM(S): Mus musculus 
2010-07-10 | E-GEOD-20867 | biostudies-arrayexpress
TranscriptomicsRoles of mammalian Rap1 in TERT recruitment to chromatin, subtelomeric gene silencing and transcriptional regulation
Repressor-activator protein 1 (scRap1) is the major binding activity at Saccharomyces cerevisiae telomeres, with roles in telomere length regulation and establishment of subtelomeric silencing by recruiting the Sir proteins. scRap1 also acts as a transcription factor controlling the expression of ri...
ORGANISM(S): Mus musculus 
2010-07-10 | E-GEOD-19011 | biostudies-arrayexpress
UnknownGeographic genetic variation in the Coral Hawkfish, Cirrhitichthys oxycephalus (Cirrhitidae), in relation to biogeographic barriers across the Tropical Indo-Pacific.
Not available
S-EPMC11438443 | biostudies-literature
TranscriptomicsWhole genome analysis of p38 SAPK-mediated gene expression upon stress
Cells have the ability to respond and adapt to environmental changes through the activation of stress-activated protein kinases (SAPKs). Although it has been shown that p38 SAPK signalling participates in the regulation of gene transcription, there is not a comprehensive genome-wide transcription st...
ORGANISM(S): Mus musculus 
2010-09-29 | E-GEOD-18320 | biostudies-arrayexpress
UnknownA Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells.
Not available
S-EPMC6409439 | biostudies-literature
UnknownEfficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.
Not available
S-EPMC5731244 | biostudies-literature
UnknownComparative genomics reveals insights into avian genome evolution and adaptation.
Not available
S-EPMC4390078 | biostudies-literature
UnknownClinical and genetic delineation of autosomal recessive and dominant ACTL6B-related developmental brain disorders.
Not available
S-EPMC12042808 | biostudies-literature
UnknownGenome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.
Not available
S-EPMC5711884 | biostudies-literature
UnknownA communal catalogue reveals Earth's multiscale microbial diversity.
Not available
S-EPMC6192678 | biostudies-literature
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