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TranscriptomicsGene Expression Profiles of MYC+ and MYC- mouse Germinal Center B cells
Germinal centers (GC) arise within B cell follicles upon antigenic challenge. In the dark zones (DZ) of GCs, B cells proliferate and hypermutate their immunoglobulin genes, and mutants with increased affinity are positively selected in the light zone (LZ) to either differentiate into plasma and memo...
ORGANISM(S): Mus musculus 
2012-09-24 | E-GEOD-38304 | biostudies-arrayexpress
TranscriptomicsExpression profiles of murine FOXO1+/+ and FOXO1-null GC B cells
The pathways regulating the formation of the germinal center (GC) dark- (DZ) and light- (LZ) zones are unknown. We show that FOXO1 expression is restricted to the GC DZ and is required for DZ formation, since its absence in mice leads to the complete loss of DZ gene programs and the formation of LZ-...
ORGANISM(S): Mus musculus 
2015-12-04 | E-GEOD-69216 | biostudies-arrayexpress
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
UnknownObservation of quantum entanglement with top quarks at the ATLAS detector.
Not available
S-EPMC11410654 | biostudies-literature
UnknownRepurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
Not available
S-EPMC7727327 | biostudies-literature
UnknownComparative effectiveness of immediate antiretroviral therapy versus CD4-based initiation in HIV-positive individuals in high-income countries: observational cohort study.
Not available
S-EPMC4643831 | biostudies-literature
UnknownSearch for heavy neutrinos and [Formula: see text] bosons with right-handed couplings in proton-proton collisions at [Formula: see text].
Not available
S-EPMC4371073 | biostudies-literature
UnknownSearch for supersymmetry in pp collisions at [Formula: see text] TeV in events with a single lepton, jets, and missing transverse momentum.
Not available
S-EPMC4370766 | biostudies-literature
UnknownMeasurement of the differential cross section for top quark pair production in pp collisions at [Formula: see text].
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S-EPMC4657759 | biostudies-literature
UnknownElliptic anisotropy measurement of the f<sub>0</sub>(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition.
Not available
S-EPMC12391314 | biostudies-literature
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