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MetabolomicsEvaluation of significant features discovered from different data acquisition modes in mass spectrometry-based untargeted metabolomics

Despite the growing popularity of liquid chromatography-mass spectrometry (LC-MS)-based metabolomics, no study has yet to systematically compare the performance of different data acquisition modes in the discovery of significantly altered metabolic features, which is an important task of untarget...

2020-10-02 | MTBLS1842 | MetaboLights
UnknownMolecular characteristics and clinical outcomes of complex ALK rearrangements identified by next-generation sequencing in non-small cell lung cancers.
Not available
S-EPMC8283930 | biostudies-literature
UnknownRadiomic features from multiparametric magnetic resonance imaging predict molecular subgroups of pediatric low-grade gliomas.
Not available
S-EPMC10496393 | biostudies-literature
UnknownRNA sequencing reveals the expression profiles of circRNA and identifies a four-circRNA signature acts as a prognostic marker in esophageal squamous cell carcinoma.
Not available
S-EPMC7934454 | biostudies-literature
MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
TranscriptomicsGenome-wide transcriptome analysis of two maize inbred lines under drought stress during the seedling stage
To understand the transcriptome changes during drought tolerance in maize, the drought-tolerant line Han21 and drought-sensitive line Ye478, which show substantial differences in drought tolerance at the seedling stage, were selected for this study. Using the GeneChip Maize Genome Arrays, we applied...
ORGANISM(S): Zea mays 
2010-06-16 | E-GEOD-16567 | biostudies-arrayexpress
UnknownGlycolysis-related biomarker TCIRG1 participates in regulation of renal cell carcinoma progression and tumor immune microenvironment by affecting aerobic glycolysis and AKT/mTOR signaling pathway.
Not available
S-EPMC10468907 | biostudies-literature
MetabolomicsSerum organic acid metabolites can be used as potential biomarkers to identify prostatitis, benign prostatic hyperplasia, and prostate cancer (Untargeted assay)

BACKGROUND: Noninvasive methods for the early identify diagnosis of prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer (PCa) are current clinical challenges.

METHODS: The serum metabolites of 20 healthy individuals and patients with prosta...

2023-04-17 | MTBLS6039 | MetaboLights
UnknownRetinal features as predictive indicators for high myopia: insights from explainable multi-machine learning models.
Not available
S-EPMC12555007 | biostudies-literature
UnknownImpacts of COVID-19 on global stock sectors: Evidence from time-varying connectedness and asymmetric nexus analysis
Not available
S-EPMC9252869 | biostudies-literature
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