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ProteomicsColonic smooth-muscle BIN1 and ALDH1B1 loss triggers mitochondrial dysfunction and fibrosis in slow-transit constipation
Slow-transit constipation (STC) is a debilitating disorder of colonic motility with poorly defined molecular underpinnings. While abnormalities in the enteric nervous system and interstitial cells of Cajal have been extensively studied, smooth-muscle–intrinsic mechanisms remain largely unexplored. H...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD069723 | Pride
Mitochondrial function  fibrosis  intestinal motility 
UnknownImpaired migration and lung invasion of human melanoma by a novel small molecule targeting the ...
Not available
S-SCDT-10_1038-S44321-025-00297-1 | biostudies-other
ProteomicsImmune response pattern across the asymptomatic, symptomatic and convalescent periods of COVID-19
We present an integrated analysis of urine and serum proteomics and clinical measurements in asymptomatic, mild/moderate, severe and convalescent cases of COVID-19. We identify the pattern of variation of immune response proteins during COVID-19 infection. The immune response is activated in asympto...
ORGANISM(S): Homo Sapiens 
2021-06-03 | PXD026442 |
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