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UnknownStructure of the putative dihydroorotate dehydrogenase from Streptococcus mutans.
Not available
S-EPMC3034605 | biostudies-literature
UnknownStructure of the human sulfhydryl oxidase augmenter of liver regeneration and characterization of a human mutation causing an autosomal recessive myopathy .
Not available
S-EPMC2914844 | biostudies-literature
TranscriptomicsRotenone susceptibility phenotype in olfactory derived patient cells as a model of idiopathic Parkinson’s disease
Physiologically relevant cellular models are critical for understanding complex pathological processes. Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterised by motor and non-motor symptoms. Several cellular models for PD have been developed to reproduce the a...
ORGANISM(S): Homo sapiens 
2016-10-04 | E-MTAB-4164 | biostudies-arrayexpress
TranscriptomicsConA-induced fulminant hepatitis in a mouse model
The goal of this experiment was to investigate the early mechanisms of human fulminant hepatitis through ConA-induced hepatitis model.Early diagnosis and interventions are important for patients with fulminant hepatitis and gene expression may be pivotal in the early diagnosis. Keyword :ConA-induc...
ORGANISM(S): Mus musculus 
2009-07-21 | E-GEOD-17184 | biostudies-arrayexpress
TranscriptomicsGeneration of integration-free induced hepatocytes from mouse fibroblasts
Previous studies demonstrated that hepatocyte-specific transcription factors could directly convert fibroblasts into functional hepatocytes-like cells, namely induced hepatocytes (iHeps) using viral systems. However, viral integration into host genome causes insertional mutation and risk of tumorige...
ORGANISM(S): Mus musculus 
2015-03-27 | E-GEOD-67362 | biostudies-arrayexpress
TranscriptomicsExpression profiling of primary leukemia initiating cell-enriched population induced by AML1-ETO9a
Combined gene expression and DNA occupancy profiling identifies JAK/STAT signaling as a valid therapeutic target of t(8;21) AML t(8;21) is commonly associated with acute myeloid leukemia (AML). The resulting AML1-ETO fusion proteins are involved in the pathogenesis of AML. To identify novel molecul...
ORGANISM(S): Mus musculus 
2012-09-04 | E-GEOD-15195 | biostudies-arrayexpress
TranscriptomicsGlobal Transcriptional Analysis of Nuclear Reprogramming in the Transition from MEFs to iPSCs
Here, we focused on the intermediate stages of SCR by comparing the somatic cell line induced by OCT4, SOX2, and KLF4 (OSK) for 7 days with mouse embryonic fibroblasts (MEFs), iPSCs, and embryonic stem cells (ESCs). Transcriptional profiles of these four cell lines were analyzed by microarray, and w...
ORGANISM(S): Mus musculus 
2012-10-01 | E-GEOD-37397 | biostudies-arrayexpress
GenomicsChIP-seq of FLAG-tagged SMARCAD1 in female mouse embryonic stem cells (PGK12.1 XX)
To understand the role of the SWI/SNF-like ATP-dependent chromatin remodeller SMARCAD1 in pluripotent murine embryonic stem (ES) cells we determined the genome wide binding of triple FLAG tagged SMARCAD1 in PGK12.1 XX ES cells. ChIP was carried out using an antibody against the FLAG-epitope (F1804, ...
ORGANISM(S): Mus musculus 
2019-02-17 | E-MTAB-7014 | biostudies-arrayexpress
UnknownMicroRNA-126 induces autophagy by altering cell metabolism in malignant mesothelioma.
Not available
S-EPMC5095004 | biostudies-literature
UnknownIncreased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade.
Not available
S-EPMC9479603 | biostudies-literature
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