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UnknownDiscovery of SHR2415, a Novel Pyrrole-Fused Urea Scaffold ERK1/2 Inhibitor.
Not available
S-EPMC9014502 | biostudies-literature
UnknownDiscovery of SHR0687, a Highly Potent and Peripheral Nervous System-Restricted KOR Agonist.
Not available
S-EPMC7667827 | biostudies-literature
UnknownDiscovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis.
Not available
S-EPMC8080595 | biostudies-literature
MetabolomicsProfiling the metabolome of uterine fluid for early detection of ovarian cancer

Ovarian cancer (OC) causes high mortality in women because of ineffective biomarkers for early diagnosis. Here, we perform metabolomics analysis on an initial training set of uterine fluid from 96 gynecological patients. A seven-metabolite-marker panel consisting of vanillylmandelic acid, norepin...

2023-03-06 | MTBLS4861 | MetaboLights
ProteomicsProteomic analysis of developing grains in the wheat under drought stress
In this study, we performed the first dynamic proteome analysis of developing grains in the wheat-Thinopyrum intermedium 7XL/7DS translocation line under drought stress using a two-dimensional difference gel electrophoresis (2D-DIGE) based proteomic approach.
ORGANISM(S): Triticum Aestivum 
2021-11-28 | PXD030025 |
ProteomicsThe mechanism of TRIM21 inhibiting the invasion and migration of ccRCC by stabilizing ASS1
Clear cell renal cell carcinoma (ccRCC) is characterized by its aggressive invasion and metastasis, posing significant clinical challenges. Understanding the molecular mechanisms underlying its progression is crucial for developing effective therapeutic strategies. The role of TRIM21 in regulating A...
ORGANISM(S): Homo Sapiens 
2024-08-13 | PXD054847 |
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