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UnknownRPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Not available
S-EPMC4124035 | biostudies-literature
TranscriptomicsWee1 Inhibition sensitizes prostate cancer cells to Hsp90 inhibitor to activate the intrinsic apoptotic pathway
Heat shock protein 90 (Hsp90) is an essential evolutionarily conserved molecular chaperone in eukaryotes. Cancer cells rely on Hsp90 to chaperone activated oncoproteins, and its involvement in numerous signaling pathways makes it an attractive target for drug development. Surprisingly, however, the ...
ORGANISM(S): Homo sapiens 
2013-01-10 | E-GEOD-38972 | biostudies-arrayexpress
UnknownInterferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming.
Not available
S-EPMC9380486 | biostudies-literature
GenomicsUC
WTCCC2 project Ulcerative Colitis (UC) samples
EGAD00000000025 | EGA
GenomicsWTCCC2 case-control study for Ulcerative Colitis
WTCCC2 project genome-wide case-control association study for Ulcerative Colitis (UC) using the 1958 British Birth Cohort and the UK National Blood Service collections as controls.
EGAS00000000084 | EGA
GenomicsWTCCC2 project controls - 1958 British Birth Cohort and National Blood Service
WTCCC2 project controls - 1958 British Birth Cohort and National Blood Service
EGAS00000000028 | EGA
UnknownPharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
Not available
S-EPMC4220464 | biostudies-literature
Genomicsena-DATASET-GoT2D/T2D-GENES-08-07-2016-21:22:44:693-1130 - samples
The T2D-GENES/GoT2D 13K exome sequencing study includes ~13,000 samples, half T2D cases and half T2D controls, from five ancestries (~5K Europeans, ~2K each of African-American, East-Asian, South-Asian, and Hispanic). Samples underwent deep exome sequencing, with SNVs and INDEls called according to ...
EGAD00001002246 | EGA
UnknownThe genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
Not available
S-EPMC5042863 | biostudies-literature
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
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