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TranscriptomicsCell surface markers that distinguish human beta cells and alpha cells
The goal of this experiment is to determine cell surface markers that are present in human beta cells or alpha cells but not both. Cells from human islets were FACS sorted and prepared as matched pairs of beta and alpha cells preparations.
ORGANISM(S): Homo sapiens 
2011-06-10 | E-MTAB-459 | biostudies-arrayexpress
TranscriptomicsDifferential expression of sorted Alpha and Beta cells
The goal of this experiment is to identify genes differentially expressed in FACS-sorted Alpha and Beta cells.
ORGANISM(S): Homo sapiens 
2011-07-23 | E-MTAB-465 | biostudies-arrayexpress
TranscriptomicsDifferential expression of representative sorted pancreatic cells
The goal of this experiment is to identify genes differentially expressed in representative pancreatic FACS-sorted cell types.
ORGANISM(S): Homo sapiens 
2011-07-26 | E-MTAB-463 | biostudies-arrayexpress
TranscriptomicsEpigenomic plasticity enables human pancreatic alpha to beta cell reprogramming
Insulin-secreting β cells and glucagon-secreting α cells maintain physiological blood glucose levels, and their malfunction drives diabetes development. Using ChIP sequencing and RNA sequencing analysis, we determined the epigenetic and transcriptional landscape of human pancreatic α, β, and exocrin...
ORGANISM(S): Homo sapiens 
2013-08-28 | E-GEOD-50386 | biostudies-arrayexpress
TranscriptomicsProspective isolation of a bipotential clonogenic liver progenitor cell in adult mice
The molecular identification of adult hepatic stem/progenitor cells has been hampered by the lack of truly specific markers. To isolate putative adult liver progenitor cells, we used cell surface-marking antibodies, including MIC1-1C3, to isolate subpopulations of liver cells from normal adult mice ...
ORGANISM(S): Mus musculus 
2011-05-07 | E-GEOD-29121 | biostudies-arrayexpress
UnknownIntegrative analysis of large scale transcriptome data draws a comprehensive landscape of Phaeodactylum tricornutum genome and evolutionary origin of diatoms.
Not available
S-EPMC5859163 | biostudies-literature
TranscriptomicsFoxl1-Cre-marked Adult Hepatic Progenitors Have Clonogenic and Bi-Lineage Differentiation Potential - Time Course
The winged helix transcription factor Foxl1 is a marker for progenitor cells and their descendants in the mouse liver in vivo. Here, we purify progenitor cells from Foxl1-Cre; RosaYFP mice and evaluate their proliferative and differentiation potential in vitro. Treatment of Foxl1-Cre; RosaYFP mice w...
ORGANISM(S): Mus musculus 
2011-05-01 | E-GEOD-28890 | biostudies-arrayexpress
TranscriptomicsFoxl1-Cre-marked Adult Hepatic Progenitors Have Clonogenic and Bi-Lineage Differentiation Potential
The winged helix transcription factor Foxl1 is a marker for progenitor cells and their descendants in the mouse liver in vivo. Here, we purify progenitor cells from Foxl1-Cre; RosaYFP mice and evaluate their proliferative and differentiation potential in vitro. Treatment of Foxl1-Cre; RosaYFP mice w...
ORGANISM(S): Mus musculus 
2011-05-01 | E-GEOD-28892 | biostudies-arrayexpress
TranscriptomicsFoxl1-Cre-marked Adult Hepatic Progenitors Have Clonogenic and Bi-Lineage Differentiation Potential - Differentiated vs Primary
The winged helix transcription factor Foxl1 is a marker for progenitor cells and their descendants in the mouse liver in vivo. Here, we purify progenitor cells from Foxl1-Cre; RosaYFP mice and evaluate their proliferative and differentiation potential in vitro. Treatment of Foxl1-Cre; RosaYFP mice w...
ORGANISM(S): Mus musculus 
2011-05-01 | E-GEOD-28891 | biostudies-arrayexpress
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