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ProteomicsProfiling Cullin4-E3 ligases interactomes and their rewiring in influenza A virus infection
Understanding the integrated regulation of cellular processes during viral infection is crucial for developing host-targeted approaches. We have previously reported that an optimal in-vitro infection by influenza A (IAV) requires three components of Cullin 4-RING E3 ubiquitin ligases (CRL4), namely ...
ORGANISM(S): Homo sapiens (Human) Influenza A virus (A/WSN/1933(H1N1)) 
2025-05-06 | PXD050261 | Pride
Human Ap-ms Q exactive plus Influenza virus 
ProteomicsThe role of the Ser/Thr kinase PrkC of Clostridium difficile in cell wall homeostasis and antimicrobial resistance.
Clostridium difficile is the leading cause of antibiotic associated diarrhea in adults. During infection, the bacteria must rapidly respond and adapt to the host environment by being able to activate survival strategies. Ser/Thr kinases (STKs) are involved in signal transduction and regulate numerou...
ORGANISM(S): Clostridioides difficile 
2019-06-14 | PXD012241 | Pride
Qexactive hf Clostridium difficile Cell wall Shotgun proteomics 
ProteomicsQuantitative analysis of differential proteome expression in wild-type and mutants strains of Salmonella enterica serovar Typhimurium
The ability to adapt quickly to changing environmental conditions is crucial for growth and survival of bacteria in their natural environment. The common strategy that bacteria utilize to increase their survival under stressful conditions, including antibiotic treatment, is the entry into a non-acti...
ORGANISM(S): Salmonella typhimurium (strain 14028s / SGSC 2262) 
2018-10-26 | PXD005256 | Pride
Perseus Shotgun proteomics Q exactive hf Salmonella enterica serovar typhimurium Maxquant 
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