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TranscriptomicsTranscription profiling of S. cerevisiae in response to doxycycline treatment to investidate the role of doxycycline on global gene expression in yeast
Not available
ORGANISM(S): Saccharomyces cerevisiae 
2005-05-01 | E-MAXD-3 | biostudies-arrayexpress
TranscriptomicsButyrate Induced Changes in Wnt Signaling-Specific Gene Expression in Colorectal Cancer Cells
To identify Wnt target genes whose expression is differentially modulated by butyrate Doxycycline inducible DN-Tcf4 expression was used to repress Wnt signaling, cells were treated with butyrate or mock treated. Genes differentially regulated by butyrate in the absence of doxycycline but not in its...
ORGANISM(S): Homo sapiens 
2014-01-16 | E-GEOD-54127 | biostudies-arrayexpress
TranscriptomicsshRNAi profiling of huuman CHD8 depleted cells
CHD8 is a putative chromatin remodeling ATPase of the SNF2 family. We found that depletion of CHD8 impairs cell proliferation. In order to identify CHD8 target genes, we performed a transcriptomic analysis of CHD8-depleted cells. CHD8 was knockdown by doxycyclin-dependent expression of a shRNA that ...
ORGANISM(S): Homo sapiens 
2009-05-14 | E-GEOD-11422 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of untreated and doxycycline-treated HeLa/TO-SmN
Purpose is to examine the effect of SmN expression to gene expression in HeLa Compare the differences between the transcriptome of untreated and doxycycline-treated HeLa/TO-SmN in which expression of SmN is under doxycycline control
ORGANISM(S): Homo sapiens 
2015-01-16 | E-GEOD-54136 | biostudies-arrayexpress
TranscriptomicsExpression analysis of doxycycline inducible secondary fibroblasts reprogramming under adherent and suspension conditions
Samples of adherent and suspension cells undergoing reprogramming were collected at day 0, day2, day6, day15 (with doxycycline) and day25 (without doxycycline). Reprogramming under adherent and suspension conditions was compared by PCC analysis, non-hierarchical clustering and by functional criteria...
ORGANISM(S): Mus musculus 
2012-03-25 | E-GEOD-35422 | biostudies-arrayexpress
TranscriptomicsGene expression in cells expressing doxycycline-induced thymidylate synthase transgene
Gene expression was compared between a Tet-OFF transfomant expressing thymidylate synthase trasgene and its parental human colorectal cancer cell line, DLD-1, or the transformant exposed to doxycycline.
ORGANISM(S): Homo sapiens 
2015-03-31 | E-MTAB-3414 | biostudies-arrayexpress
TranscriptomicsExpression data from β-globin let7 HeLa tet off cells treated with doxycycline
We used microarray to determine the genes whose expression was changed at six hours after doxycycline treatment Cells were transfected with β-globin let7 wt constructs. Two-condition experiment; HeLa tet off cells overexpressed control vs HeLa tet off cells treated with doxycycline for six hours
ORGANISM(S): Homo sapiens 
2016-03-15 | E-GEOD-66541 | biostudies-arrayexpress
TranscriptomicsZXDA dependent transcription regulation in HCT116 human colon carcinoma cells upon doxycycline administration
The goal of the study was to investigate the effect of inducible ZXDA expression in HCT116 cell line. HCT116 clones expressing inducible versions of human ZXDA gene (2 clones wild-type; 2 clones ERP386-388AAA) were incubated with or without doxycycline.
ORGANISM(S): Homo sapiens 
2022-06-15 | E-MTAB-11269 | biostudies-arrayexpress
TranscriptomicsRNA-seq in Raji cells with inducible BZLF1 prior to and after induction of EBV's lytic cycle by doxycycline
(i) RNA transcripts of Raji iBZLF1 cells (https://www.biorxiv.org/content/10.1101/573659v1) were compared between non-induced cells and cells induced with doxycycline (100 ng/ ml) for 6 h. Human (Hg19) as well as viral (EBV, Raji KF717093.1) transcripts were analyzed. Artificial ERCC Spike-ins (Ther...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-7820 | biostudies-arrayexpress
TranscriptomicsAnalysis of gene expression and splicing after doxycycline-induced knockdown of SRSF3
SRSF3 is overexpressed in human invasive ovarian cancer and its overexpression is required for cancer cell growth and survival. To decipher the mechnisms behind the role of SRSF3 in ovarian cancer, we examined the gene expression and splicing in the ovarian cancer cell line that was engineered to ex...
ORGANISM(S): Homo sapiens 
2015-08-06 | E-GEOD-71745 | biostudies-arrayexpress
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