Intronic hexanucleotide repeat expansions in the C9orf72 gene are the most common genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). These intronic hexanucleotide repeat expansions result in the production of toxic dipeptide repeat proteins (DPRs), which contribu...
ORGANISM(S): Drosophila melanogaster