Sort   by:  
 Page size 
GenomicsChIP-seq of EGR1 in human primary unstimulated monocytes and in unstimulated human monocytes from three CMML patients
Identification of EGR1 chromatin localization in human primary monocytes (2 donors), in human primary monocytes from 2 CMML patients with TET2 truncating mutations (high VAF) and in human primary monocytes from 1 CMML patients with TET2 truncating mutations with low VAF.
ORGANISM(S): Homo sapiens 
2021-11-15 | E-MTAB-11132 | biostudies-arrayexpress
GenomicsCMML Collection of WES, WGS, RNA-Seq and ERRBS data
We first performed a comprehensive analysis of the genome of 66 chronic myelomonocytic leukemia cases using whole exome (N=49) or whole genome (N=17) sequencing for paired leukemic-control DNA. Then, we realized serial analysis of whole exome sequence in 17 cases, completed with serial RNA sequencin...
EGAS00001001264 | EGA
GenomicsChIP-seq of CSF-1R in THP-1 cell lines deleted for EGR1 gene by CRISPR-Cas9 and ChIP-seq of CSF-1R in 2 CMML patients
CSF-1R is recruited on EGR1 motifs in monocytes where it colocalizes with EGR1. To address if EGR1 required for CSF-1R recruitment on chromatin, THP-1 monocytic cell line has been deleted for EGR1 by CRISPR-Cas9 approach. 3 clones were generated by single cell cloning and CSF-1R localization on chro...
ORGANISM(S): Homo sapiens 
2019-03-28 | E-MTAB-7756 | biostudies-arrayexpress
GenomicsChIP-seq of CSF-1R, H3K4me1, H3K4me3 in human primary unstimulated monocytes and monocytes differentiated 72h with CSF-1 (3 healthy donors buffy coat) and in monocytes from two CMML patients and one healthy donor, EGR1 ChIP-seq in unstimulated monocytes (3 healthy donors buffy coat)
Identification of nuclear CSF-1R, H3K4me1 and H3K4me3 localization on chromatin in human primary monocytes and modification of this localization during monocyte differentiation into macrophage induced by 100ng/mL CSF-1 during 6 hours (1 donor) or 72h (3 donors). Identification of EGR1 chromatin loc...
ORGANISM(S): Homo sapiens 
2019-03-04 | E-MTAB-6305 | biostudies-arrayexpress
TranscriptomicsRNA-seq of primary mouse monocytes from miR-150 knockout and Tet3 knockout mice compared to wild type controls
Monocytes were isolated from blood of Wildtype, Mir150 and TET3 knockout mice, sorted for classical and non-classical monocyte subsets. RNA seq was performed on unstimulated monocytes.
ORGANISM(S): Mus musculus 
2018-10-26 | E-MTAB-7291 | biostudies-arrayexpress
GenomicsChIP-Seq of H3K4me3 in primary unstimulated monocyte subsets from 2 healthy donors buffy coats
Identification of H3K4me3 localization on chromatin in primary unstimulated monocyte subsets
ORGANISM(S): Homo sapiens 
2018-11-09 | E-MTAB-7290 | biostudies-arrayexpress
TranscriptomicsRNA-seq of primary human monocytes (4 healthy donors)
Monocytes were isolated from healthy donors PBMC and sorted for classical and non-classical monocyte subsets. RNA-seq was performed on unstimulated monocytes.
ORGANISM(S): Homo sapiens 
2018-11-09 | E-MTAB-6712 | biostudies-arrayexpress
GenomicsChiP-seq of H3K4me3 in primary unstimulated monocytes from 3 healthy donors buffy coats and from 4 CMML patients
Identification of H3K4me3 localization on chromatin in primary unstimulated monocytes
ORGANISM(S): Homo sapiens 
2018-11-09 | E-MTAB-6689 | biostudies-arrayexpress
Genomicsena-DATASET-GR-05-12-2015-13:51:06:366-72 - samples
In this dataset are the data from : - 17 patients studied by WGS - 49 patients studied by WES - 9 (/49) patients studied by RNASeq at 2 time points - the same 9 patients studied by ERRBS at 2 time points
EGAD00001001853 | EGA
GenomicsGustave Roussy CMML Collection DAC
Data Access Committee EGAC00001000342
EGAC00001000342 | EGA
Sort   by:  
 Page size