Sort   by:  
 Page size 
ProteomicsGenomic regions flanking E-box sites influence DNA binding specificity of bHLH transcription factors through DNA shape (validation)
DNA sequence is a major determinant of the binding specificity of transcription factors (TFs) for their genomic targets. However, eukaryotic cells often express, at the same time, TFs with highly similar DNA binding motifs but distinct in vivo targets. Currently, it is not well understood how TFs wi...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-29 | E-GEOD-44437 | biostudies-arrayexpress
ProteomicsGenomic regions flanking E-box sites influence DNA binding specificity of bHLH transcription factors through DNA shape (different concentrations)
DNA sequence is a major determinant of the binding specificity of transcription factors (TFs) for their genomic targets. However, eukaryotic cells often express, at the same time, TFs with highly similar DNA binding motifs but distinct in vivo targets. Currently, it is not well understood how TFs wi...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-29 | E-GEOD-44436 | biostudies-arrayexpress
TranscriptomicsMolecular mechanisms of cigarette smoke-induced lung emphysema
Chronic obstructive pulmonary disease (COPD) is a complex pulmonary disorder primarily induced by cigarette smoking, and characterized by persistent airflow limitation. The mouse represents an important model for studying COPD pathologies such as lung emphysema. In this respect, a number of mechanis...
ORGANISM(S): Mus musculus 
2014-11-28 | E-MTAB-2756 | biostudies-arrayexpress
Sort   by:  
 Page size