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This study is unique in that it was the first time that it was the female response to microgravity simulated by 3-day dry immersion that was analyzed. The result of the choice of the object of research fell on dry blood spots, since the technique of capillary blood sampling is less invasive and allo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027654 | Pride
Muscle disuse results in complex signaling alterations followed by structural and functional changes, such as atrophy, force decrease and slow-to-fast fiber-type shift. Little is known about human skeletal muscle signaling alterations under long-term muscle disuse. In this study, we describe the eff...
ORGANISM(S): Homo sapiens 
2025-03-22 | GSE268033 | GEO
Rapid changes in transcriptomic profile and mitochondrial function in human soleus muscle after three-day dry immersion
We aimed to explore the effect of the 3-day dry immersion - a model of physical unloading - on mitochondrial function, transcriptomic and proteomic profiles in a slow-twitch m. soleus of six healthy females. We registered that a marked reduction (25-34%) in the ADP-stimulated respiration in permeabi...
ORGANISM(S): Homo sapiens 
2022-11-02 | GSE216845 | GEO
Molecular insights into human soleus muscle atrophy development: long-term dry immersion effects on the transcriptomic profile and post-translational signaling
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