Dsrnas - OmicsDI

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Architecture et Réactivité de l’ARN, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire du CNRS, 67084 Strasbourg, France (1)
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RIDI UPR 9022, Université de Strasbourg, Centre National de la Recherche Scientifique, F-67000, France. (1)
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Endocytosed dsRNAs induce lysosomal membrane permeabilization that allows cytosolic dsRNA translocation for Drosophila RNAi response

PRJNA1023479 | ENA

Endocytosed dsRNAs induce lysosomal membrane permeabilization that allows cytosolic dsRNA translocation for Drosophila RNAi response

RNA interference (RNAi) is a gene-silencing mechanism triggered by the cytosolic entry of double-stranded RNAs (dsRNAs). Many animal cells internalize extracellular dsRNAs via endocytosis for RNAi induction. However, it is not clear how the endocytosed dsRNAs are translocated into the cytosol across...

ORGANISM(S): Drosophila melanogaster

2024-07-07 | GSE244523 | GEO

Small dsRNAs induce transcriptional activation in human cells.

Not available

S-EPMC1859931 | biostudies-literature

PTGS induced by different dsRNAs

Unexpected variations in posttranscriptional silencing induced by differentially produced dsRNAs

PRJEB33605 | ENA

Evidence of off-target effects associated with long dsRNAs in Drosophila cell-based assays

To evaluate the specificity of long dsRNAs used in high-throughput RNAi screens performed at the Drosophila RNAi Screening Center (DRSC), we performed a global analysis of their activity in 30 genome-wide screens completed at our facility. Surprisingly, our analysis predicts that dsRNAs containing ≥...

ORGANISM(S): Drosophila melanogaster

2006-08-18 | GSE5554 | GEO

Effect of p53 on the expression of combo induced dsRNAs in 2153L GEM tumors

PRJNA1156765 | ENA

Endocytosed dsRNAs induce lysosomal membrane permeabilization that allows cytosolic dsRNA translocation for Drosophila RNAi responses.

Not available

S-EPMC11324899 | biostudies-literature

ADAR1 editing is necessary for only a small subset of cytosolic dsRNAs to evade MDA5-mediated autoimmunity.

Not available

S-EPMC12695637 | biostudies-literature

Feasibility of Systemically Applied dsRNAs for Pest-Specific RNAi-Induced Gene Silencing in White Oak.

Not available