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MetabolomicsSupplementation of Bacillus sp. DU-106 reduces hypercholesterolemia and ameliorates gut dysbiosis in high-fat diet rats

Gut microbiota modulation by a probiotic is a novel therapy for hypercholesterolemia mitigation. This study initially investigated the potential hypocholesterolemic effect of Bacillus sp. DU-106 in hypercholesterolemic rats and explored its potential relation with gut microbiota. Sprague-Dawley r...

2021-04-08 | MTBLS1168 | MetaboLights
GenomicsExpression data upon K-Ras elimination in DU, DU RRAS2 G23V and DU PI3KCAAX cells
Expression data upon K-Ras elimination in DU, DU RRAS2 G23V and DU PI3KCAAX cells
PRJNA1078787 | ENA
TranscriptomicsUnexpected complexity of the Escherichia coli K-12 transcriptome architecture revealed by single nucleotide resolution RNA sequencing
To investigate the architecture of the E. coli K-12 transcriptome, we used two RNA-Seq technologies to analyze strand-specific transcription at single-nucleotide resolution. We analyzed the data by using an organizational schema to annotate the promoters and terminators that define transcription uni...
ORGANISM(S): Escherichia coli K-12 
2014-07-08 | E-GEOD-52059 | biostudies-arrayexpress
GenomicsLymph miRNA in FcgRIIA transgenic mice, in K/BxN rheumatoid arthritis
Lymph miRNA in FcgRIIA transgenic mice, in K/BxN rheumatoid arthritis
PRJEB33651 | ENA
TranscriptomicsRNA expression analysis after DU-145 cell treatment with demethylating agent 5-Aza-2’-deoxycitidine (5-Aza)
Transcriptional profiling of DU-145 cells treated with 5-Aza for 72 h. Relative abundance to untreated control cells was used to estimate the effect of DNA demethylation on the expression of the RNAs. Two-condition experiment, 5-Aza-treated vs. untreated DU-145 cells. Biological replicates: 2. Techn...
ORGANISM(S): Homo sapiens 
2015-06-30 | E-GEOD-62955 | biostudies-arrayexpress
UnknownStructural basis of collagen fiber degradation by cathepsin K.
Not available
S-EPMC4267343 | biostudies-literature
TranscriptomicsWithaferin A (WA) causes cell death in prostate cells.
Withaferin A (WA), a major chemical component of an Indian herb Withania somnifera, induces cell death (apoptosis/necrosis) in a variety of tumor cells, but its molecular mechanism remains elusive. We report that WA induces cell death selectively in high-grade prostate (PC-3 and DU-145) and tongue (...
ORGANISM(S): Homo sapiens 
2015-08-02 | E-GEOD-55728 | biostudies-arrayexpress
UnknownPalytoxin acts on Na(+),K (+)-ATPase but not nongastric H(+),K (+)-ATPase.
Not available
S-EPMC2396460 | biostudies-literature
TranscriptomicsmiRNA expression in LNCaP, PC3, Du-145 and RWPE-1 cell lines
MiRNAs are small non-coding RNAs that regulate the expression of specific mRNA targets mainly by translational repression, mRNA deadenylation or cleavage. This series is meant to identify miRNAs deregulated in prostate cancer (PCa) by comparing the PCa cell lines LNCaP, PC3 and Du-145 to the normal ...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-17317 | biostudies-arrayexpress
UnknownStructure Reassignment of Cryptorigidifoliols E and K.
Not available
S-EPMC5825288 | biostudies-literature
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