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ProteomicsAMBRA1 controls the translation of immune-specific genes in T lymphocytes
T cell receptor (TCR) engagement causes a global cellular response that entrains signaling pathways, cell cycle regulation, and cell death. The molecular regulation of mRNA translation in these processes is poorly understood. During a whole-genome CRISPR screen for regulators of CD95 (Fas/APO-1)-med...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-08 | MSV000096042 | MassIVE
Proteomicsmetabolic reprogramming induced by LONP1 in prostate cancer is closely coupled with disease progression
To understand how Lon protease 1(Lonp1) knockin promotes prostate cancer metastasis in vivo, we performed proteomic analysis on prostates extracted from 40-week-old wild-type (WT), Lonp1KI, Pten-/- and Pten-/-; Lonp1KI mice.
ORGANISM(S): Mus Musculus 
PXD053059 |
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