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TranscriptomicsEAG2 potassium channel with evolutionarily conserved function as a brain tumor target
Characterizing the impact of pharmacological and shRNA-mediated silencing of EAG2 in medulloblastoma. A medulloblastoma (MB) cell line was untreated, mock(DMSO)-treated and treated to inhibit EAG2 (both pharmacologically and via shRNA).
ORGANISM(S): Homo sapiens 
2015-07-08 | E-GEOD-70576 | biostudies-arrayexpress
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
TranscriptomicsClonal Selection Drives Genetic Divergence of Metastatic Medulloblastoma [Illumina Infinium HumanMethylation27 Beadchip v1.2]
Medulloblastoma, the most common malignant pediatric brain tumour, disseminates by shedding cells into the cerebrospinal fluid, which then re-implant to cover the surface of the brain and spinal cord. Metastases are a very poor prognostic sign at presentation and are usually lethal at recurrence. ...
ORGANISM(S): Homo sapiens 
2011-12-13 | E-GEOD-34355 | biostudies-arrayexpress
TranscriptomicsDNA methylation of matched primary-metastases medulloblastomas
DNA methylation was generated from 11 pairs of matched primary-metastases medulloblastoma samples using the Illumina Infinium HumanMethylation450 BeadChip array Total DNA was extracted from primary and metastases medulloblastoma samples, bisulfite converted and hybridized to Illumina Infinium HumanM...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-63669 | biostudies-arrayexpress
TranscriptomicsHigh-resolution copy number analysis of medulloblastoma
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the genome of 212 medulloblastomas, a malignant pediatric brain tumor. Focal amplifications of fifteen known oncogenes and focal deletions of twenty known tumor suppressor genes (TSG) were revealed, most not prev...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-14437 | biostudies-arrayexpress
TranscriptomicsRIP-Chip analysis of Musashi (Msi1) in the Daoy human medulloblastoma cell line.
RIP-chip analysis to identify mRNA preferentially associated with Msi1 protein. RIP-Chip experiments were performed on two biologically replicated samples transfected with the BAP-Msi1 construct and a control sample from cells transfected with the BAP-Control construct. A total of 8 microarrays were...
ORGANISM(S): Homo sapiens 
2011-07-25 | E-GEOD-30904 | biostudies-arrayexpress
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