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TranscriptomicsEffects of tocilizumab versus methotrexate therapy on gene expression profiles in the early rheumatoid arthrtis synovium
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disease that is characterized by the presence of inflammatory cytokines, including interleukin-6 (IL-6). Here, we investigated the global molecular effects of Tocilizumab, an approved humanized anti-IL6 Receptor antibody, versu...
ORGANISM(S): Homo sapiens 
2013-12-30 | E-GEOD-45867 | biostudies-arrayexpress
TranscriptomicsDown-regulation of Interferon signature in systemic lupus erythematosus patients by active immunization with Interferon alpha-Kinoid extended follow-up
Interferon-alpha Kinoid (IFN-K) is a therapeutic vaccine composed of IFN-alpha2b coupled to a carrier protein. In a phase I/II placebo-controlled trial, we observed that IFN-K significantly decreases the IFN gene signature in whole blood RNA samples from SLE patients (see GSE39088). Here, we analyze...
ORGANISM(S): Homo sapiens 
2016-02-29 | E-GEOD-72754 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pigmented and non-pigmented tubers of Solanum tuberosum
Transcriptional analysis of pigmented and non-pigmented potato tuber flesh using POCI 44k microarrays
ORGANISM(S): Solanum tuberosum 
2010-01-01 | E-TABM-787 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pigmented and non-pigmented tubers of Solanum tuberosum
Transcriptional analysis of pigmented and non-pigmented potato tuber flesh using POCI 44k microarrays
ORGANISM(S): Solanum tuberosum 
2010-01-01 | E-TABM-788 | biostudies-arrayexpress
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