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GenomicsIntegrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells [ChIP-Seq data]
We profiled two repressive histone modifications (H3K9m3 and H3K27m3) using ChIP-Seq in normal urothelial cells and cell lines representing non-invasive and invasive tumors. Two bladder cancer cell lines (RT112 and EJ/T24 from ATCC) and normal human urothelial (NHU) cells were treated according to s...
ORGANISM(S): Homo sapiens 
2011-08-03 | E-GEOD-31125 | biostudies-arrayexpress
TranscriptomicsHypermethylation of CpG Islands and Shores adjacent to mirtron and microRNA genes in bladder cancer
We examined mirtron and miR expression in bladder cancer cell line following DNA Methyltransferase inhibition and normal urothelium using human Agilent microRNA microarrays. Bladder cancer cell lines (EJ, RT4 and RT112) were treated with 5-azacytidine ''Aza'' (2uM) for 5-7 days and normal urothelium...
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-22380 | biostudies-arrayexpress
TranscriptomicsGlobal methylation in normal and malignant urothelial cells
We have created 5-methylcytosine profiles for normal and malignant urothelial cells. Competitive hybridization of background and 5-methylcytosine enriched immunoprecipiated DNA fractions
ORGANISM(S): Homo sapiens 
2011-09-19 | E-GEOD-31865 | biostudies-arrayexpress
TranscriptomicsIntegrated epigenome profiling of DNA methylation and gene expression in normal and malignant urothelial cells
This SuperSeries is composed of the following subset Series: GSE31864: Epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells GSE31865: Global methylation in normal and malignant urothelial cells Refer to individual Serie...
ORGANISM(S): Homo sapiens 
2011-09-19 | E-GEOD-31866 | biostudies-arrayexpress
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