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TranscriptomicsATACseq : role of trisomy 21, GATAs mutation and associated mutations in the development of trisomy 21
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modelled this leukemic evolution through ...
ORGANISM(S): Homo sapiens 
2022-06-15 | E-MTAB-11044 | biostudies-arrayexpress
GenomicsRole of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: Cut&Tag
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modelled this leukemic evolution through ...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-11032 | biostudies-arrayexpress
TranscriptomicsRole of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: RNAseq
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modeled this leukemic evolution through s...
ORGANISM(S): Homo sapiens 
2022-09-29 | E-MTAB-11033 | biostudies-arrayexpress
TranscriptomicsRole of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: Single cell RNAseq
Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. We modelled this leukemic evolution through ...
ORGANISM(S): Homo sapiens 
2022-09-29 | E-MTAB-11036 | biostudies-arrayexpress
TranscriptomicsSigX ECF sigma factor deletion mutant expression profile in Pseudomonas aeruginosa in M9 minimal medium (M9G)
Analysis of a SigX knockout mutant of Pseudomonas aeruginosa H103 strain in minimal medium with glucose as carbon source (M9G). SigX, one of the 19 extra-cytoplasmic function sigma factors of P. aeruginosa, was only known to be involved in transcription of the gene encoding the major outer membrane ...
ORGANISM(S): Pseudomonas aeruginosa 
2014-01-01 | E-GEOD-51076 | biostudies-arrayexpress
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