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TranscriptomicsTranscription profiling of human stimulate neutrophils to investigate the impact of anti-inflammatory agents on the gene expression profiles
Adenosine, prostaglandin E2, or increased intracellular cyclic AMP concentration each elicit potent anti-inflammatory events in human neutrophils by inhibiting functions such as phagocytosis, superoxide production, adhesion and cytokine release. However, the endogenous molecular pathways mediating t...
ORGANISM(S): Homo sapiens 
2009-03-28 | E-GEOD-14465 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of myeloid cells (neutrophils, macrophages and dendritic cells) isolated from the spinal cord of mice with experimental autoimmune encephalomyelitis (EAE)
We have discovered that neutrophils that infiltrate the spinal cord of mice with EAE, a model of multiple sclerosis, but not intravascular neutrophils that crawl on the luminal endothelial surface, bear on their surface the adhesion molecule Icam1. The goal of this experiment was to use Icam1 to iso...
ORGANISM(S): Mus musculus 
2017-11-10 | E-MTAB-6160 | biostudies-arrayexpress
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