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TranscriptomicsChromatin immunoprecipitation of key transcriptional regulators, RNA polymerase II and histone methylation in mouse and human liver to measure binding at regulatory regions of homologous genes
To identify experimentally both conserved and evolving aspects of transcriptional regulation, we have measured the binding of key transcriptional regulators, RNA polymerase II and histone methylation in mouse and human liver at regulatory regions of homologous genes. As expected, the set of genes f...
ORGANISM(S): Homo sapiens 
2008-05-08 | E-TABM-144 | biostudies-arrayexpress
TranscriptomicsNext generation sequencing based analysis of the embryonic (E15.5) transcriptome of wild type and β1-integrin-cKO lenses
β1-integrin is the major β-integrin subunit expressed in both lens epithelial and fiber cells. Our previous research indicated that β1-integrin is essential for the maintenance of lens epithelial integrity and survival in late embryonic lens development (Simirskii et al, 2009). Lack of β1-integrin i...
ORGANISM(S): Mus musculus 
2017-08-31 | GSE77188 | GEO
TranscriptomicsGenome-wide analysis of embryonic gene epression in the absence of Prox1 compared to wild type
Overview: We report here that gene expression in E13.5 wild type (WT) mouse lenses differs from the lenses of mice that conditionally lack the Prox1 transcription factor in the lens of their eyes (Prox1 cKO) as assayed by high throughput RNA sequencing (RNAseq). The methodology outlined herein is si...
ORGANISM(S): Mus musculus 
2016-02-04 | GSE69940 | GEO
UnknownPromoting the Positive Development of Boys in High-Poverty Neighborhoods: Evidence From Four Anti-Poverty Experiments.
Not available
S-EPMC3859244 | biostudies-literature
UnknownNovltex: A New Class of Antibiotics with Potent Activity against Multidrug-Resistant Bacterial Pathogens─Design, Synthesis, and Biological Evaluation.
Not available
S-EPMC12481569 | biostudies-literature
MetabolomicsMicrobial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans
Plant fibers in byproduct streams produced by non-harsh food processing methods represent biorepositories of diverse, naturally occurring, and physiologically active biomolecules. To demonstrate one approach for their characterization, mass spectrometry of intestinal contents from gnotobiotic mice, ...
2022-07-28 | MTBLS2331 | MetaboLights
GenomicsTranscription Factor binding evolution in five mouse species
This study aims to compar transcription factor binding region between five mouse species.
ORGANISM(S): Mus caroli 
2013-08-30 | E-MTAB-1414 | biostudies-arrayexpress
GenomicsChip-seq of three TF in Rat liver
This study aims to study genome wide location of HNF4a, FoxA1 and CEBPA in wild type rat liver. Please note that all raw data files for this study were replaced with new versions on 12 March 2014 because the previous versions are corrupted. The corrupted files are associated with ENA run accession...
ORGANISM(S): Rattus norvegicus 
2013-08-30 | E-MTAB-1415 | biostudies-arrayexpress
UnknownDe novo variants in MRTFB have gain-of-function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features.
Not available
S-EPMC11533975 | biostudies-literature
UnknownA Phase II Window of Opportunity Study of Neoadjuvant PD-L1 versus PD-L1 plus CTLA-4 Blockade for Patients with Malignant Pleural Mesothelioma.
Not available
S-EPMC9898180 | biostudies-literature
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