Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
S. cerevisiae strain FY1679 homozygous for HO deletion by KanMX4 was grown in a series of nutrient limited continuous cultures carbon, nitrogen, phosphorus and sulfur limitation to determine genes which are growth rate regulated and those which are nutrient specific regulated.
This is a reconstruction of the biochemical network of the yeast Saccharomyces cerevisiae
carried out at a jamboree organized
in April 2007 in the Manchester Centre for Integrative Systems
Biology. It is the result of a consensus merger of two previous
reconstr...