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TranscriptomicsConsequences of perinatal bisphenol A exposure in a mouse model of multiple sclerosis
Multiple sclerosis (MS) is a complex disease influenced by genetic and environmental contributing factors. Endocrine disrupting compounds (EDCs) such as bisphenol A (BPA) affect gene expression and hormone-regulated systems throughout the body. We investigated the effects of BPA on Theiler’s-virus...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-46551 | biostudies-arrayexpress
TranscriptomicsGene expression changes induced by the human aristolochic acid I in renal and hepatic tissue of mice
Aristolochic acid (AA) is the causative agent of urothelial tumours associated with aristolochic acid nephropathy and is also implicated in the development of Balkan endemic nephropathy-associated urothelial tumours. These tumours contain AA-characteristic TP53 mutations. We examined gene expression...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-18246 | biostudies-arrayexpress
TranscriptomicsGene networks and putative toxicity pathways induced by acute exposure to low dose cadmium in largemouth bass (Micropterus salmoides)
Cadmium is a natural element that can accumulate to toxic levels in the environment leading to detrimental effects in animals and humans including kidney, liver and lung injuries. Using a transcriptomics approach, genes and cellular pathways affected by a low dose of cadmium were investigated. Adul...
ORGANISM(S): Micropterus salmoides 
2014-04-02 | E-GEOD-53047 | biostudies-arrayexpress
TranscriptomicsLinkage of behavioral and genomic impacts of a wastewater effluent on the fathead minnow
Rivers containing effluents from water treatment plants are complex soups of compounds, ranging from pharmaceuticals to natural hormones. Male fathead minnows (Pimephales promelas) were exposed for 3 weeks to effluent waters from the Metropolitan Wastewater Treatment Plant in St. Paul, MN. Fish wer...
ORGANISM(S): Pimephales promelas 
2010-10-29 | E-GEOD-23490 | biostudies-arrayexpress
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