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To identify and elucidate the mechanisms of adipogenic differentiation within the mouse 3t3-l1 cell line
ORGANISM(S): Mus musculus 
Irx3 was stably knocked out using a Crispr-Cas9 system. Cells were then input into a differentiation procedure, alongside controls, and RNA was collected for all samples.
ORGANISM(S): Mus musculus 
The role of Irx3 in adipocytes was explored by knocking down gene expression of these targets in primary human adipocytes.
ORGANISM(S): Homo sapiens 
The Ewing sarcoma project aims to sequence 100 complete genomes of cells of patients suffering from this disease. It is an initiative of great projection, since this is the second most common bone tumor in children and teenagers. The goal of the project is to establish the catalogue of somatic mutat...
Ewing’s Sarcoma is a bone and soft tissue tumor that primarily affects adolescents and young adults. With current therapies, 70% of patients with localized disease survive but survival for metastatic and recurrent disease is poor. Whole genome sequencing of 19 Ewing’s Sarcoma tumors showed that STAG...
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DATA FILES FOR SJEWS-WGS
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