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We compared early biological changes in mice after inhalation exposures to cigarette smoke or e-vapor aerosols (MarkTen® cartridge with Carrier, Test-1, or Test-2 formulations; 4% nicotine). Female C57BL/6 mice were exposed to 3R4F cigarette smoke or e-vapor aerosols by nose-only inhalation for up t...
ORGANISM(S): Mus musculus 
Label free quantitative proteomics of bronchoalveolar lavage (BAL) fluid collected from rats exposed to e-cigarette aerosols (humidified air control, PG/VG, PG/VG + Nicotine, or PG/VG + Nicotine + Vanillin)
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2023-01-06 | MSV000091015 | MassIVE
Evaluation of transcriptomic responses in mouse larynx after cigarette smoke (CS) and electronic cigarette (E-Cigarette) exposures
In our lower respiratory tract, the alveolar spaces are divided from the bloodstream and the external environment by only a few microns of interstitial tissue. Alveolar macrophages (AMs) defend this delicate mucosal surface from invading infections by regularly patrolling the site. AMs have three be...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-04 | PXD050380 | Pride
Transcriptomic responses in the blood and sputum of cigarette smokers compared to e-cigarette vapers
Objectives: To identify transcriptomic differences in the blood and sputum of e-cigarette users compared to conventional cigarettes smokers and healthy controls and describe biological pathways affected by these tobacco products. Methods: Cross-sectional analysis of whole blood and sputum RNA-sequen...
ORGANISM(S): Homo sapiens 
2023-05-24 | GSE223736 | GEO
Cigarette smoking is strongly associated with various laryngeal conditions, such as laryngitis, Reinke’s edema, laryngeal leukoplakia, and laryngeal cancer. Although E-Cigarettes have emerged as a prevalent alternative to traditional cigarettes, their effects on the larynx are not thoroughly charact...
ORGANISM(S): Mus musculus 
2026-04-15 | GSE294949 | GEO
Nicotine and cigarette smoking have been previously shown to inhibit the differentiation potential and miRNA expression of human periodontal ligament derived stem cells (PDLSCs). Electronic cigarette (EC) vapor also contains nicotine, as well as other non-nicotine compounds, and, like cigarette smok...
ORGANISM(S): Homo sapiens 
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