Sort   by:  
 Page size 
MetabolomicsEarly-Life Intervention with Lactobacillus reuteri Enhances Intestinal2 Barrier Function and Resilience in Suckling Piglets via Modulation of3 Gut Microbiota and Metabolites
Early-life nutritional interventions are pivotal for promoting piglet growth and health, particularly in reducing weaning-associated disorders. This study investigated the effects of early-life Lactobacillus reuteri (L.reuteri) supplementation on growth performance, immune function, intestinal morph...
2026-03-27 | MTBLS14164 | MetaboLights
MetabolomicsAssessment of phenotypic trait plasticity in the oilseed Camelina sativa using integrated early-stage abiotic stress and field studies

Connecting the characterisation of juvenile (pre-anthesis) plant stress responses undertaken in controlled environments to field agronomic performance is a challenge. The oilseed crop Camelina sativa (camelina), with its innate resilience and plasticity, presents an opportunity to understand both...

2026-02-09 | MTBLS9839 | MetaboLights
TranscriptomicsThe Biological Residue of Low Early-Life Social Class
Research shows that children who are reared in households with low socioeconomic status are more vulnerable to heart disease, respiratory infection, and some cancers when they reach adulthood. This study conducted transcriptional profiling of PBMC in healthy adults who were low vs. high in early-lif...
ORGANISM(S): Homo sapiens 
2009-03-10 | E-GEOD-15180 | biostudies-arrayexpress
Genomicsearly life stress
early life stress Raw sequence reads
PRJNA1158309 | ENA
MetabolomicsProfiling the metabolome of uterine fluid for early detection of ovarian cancer

Ovarian cancer (OC) causes high mortality in women because of ineffective biomarkers for early diagnosis. Here, we perform metabolomics analysis on an initial training set of uterine fluid from 96 gynecological patients. A seven-metabolite-marker panel consisting of vanillylmandelic acid, norepin...

2023-03-06 | MTBLS4861 | MetaboLights
ProteomicsSex and age specific adaptations of the hippocampal proteome to early-life stress
An established limited-bedding paradigm was used to induce early-life stress in mouse pups. The hippocampus was harvested at postnatal day 21 and from adults and a non-nuclear fraction prepared for quantitative proteomic analyses using isobaric tags for relative and absolute quantitation (iTRAQ).
ORGANISM(S): Mus musculus (Mouse) 
2020-08-03 | PXD013460 | Pride
Hippocampus Proteomics Early life stress Itraq 
TranscriptomicsTo examine the influence of the early stress of maternal separation on the hippocampal transcriptome in middle-aged life
In this study, we examined the consequences of the early stress (ES) of maternal separation on hippocampal gene expression in middle-aged animals. Middle-aged (15 months old) ES animals exhibit hippocampal transcriptome changes with a significant regulation of genes associated with ion binding, tran...
ORGANISM(S): Rattus norvegicus 
2013-10-11 | E-GEOD-29414 | biostudies-arrayexpress
MetabolomicsOrganic Acids Modulate Systemic Metabolic Perturbation Caused by Salmonella Pullorum Challenge in Early-Stage Broilers
The objectives of this study were to determine the protective effects of organic acids (OA) in broilers exposed to Salmonella Pullorum challenge at early stage and to explore the potential benefits of OA by metabolomics analysis. The treatment groups included non-challenged, S. Pullorum-challenged, ...
2021-05-17 | MTBLS1274 | MetaboLights
GenomicsZygotic expression after parental early life stress
Zygotic expression after parental early life stress
PRJEB26008 | ENA
TranscriptomicsZygotic expression after parental early life stress
We performed expression analysis of 7-10 zygotes after natural mating of superovulated JaxJ naive primiparous females and males that have undergone early life stress.
ORGANISM(S): Mus musculus 
2018-10-03 | E-MTAB-6589 | biostudies-arrayexpress
Sort   by:  
 Page size