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GenomicsU373MG edaravone and carnosic acid
U373MG edaravone and carnosic acid
PRJNA529669 | ENA
TranscriptomicsU373MG edaravone and carnosic acid
We investigated the gene expression profiles of U373MG human astrocytoma cells treated with vehicle (DMSO) or edaravone or carnosic acid) or both edaravone and carnosic acid. Edaravone is a free radical scavenger sold as radicut. Carnosic acid is a phytochemical found in rosemary and sage.
ORGANISM(S): Homo sapiens 
2019-04-30 | GSE129001 | GEO
ProteomicsEdaravone Promotes Adaptive Proteomic Remodeling and Improves Behavioral Outcomes in Chronic Heat Stress–Induced Brain Injury
Background: Heat stress is an increasing global health concern associated with high mortality and multi-organ dysfunction. The brain is particularly vulnerable, leading to behavioral impairments. At the molecular level, heat stress disrupts proteins involved in synaptic communication, mitochondrial ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-06-16 | PXD079661 | Pride
Brain  heat stress  proteomics  edaravone  behavioral dysfunction. 
UnknownConfirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients.
Not available
S-EPMC4266079 | biostudies-literature
UnknownCost-effectiveness of edaravone dexborneol versus edaravone for the treatment of acute ischemic stroke in China: Based on the TASTE study.
Not available
S-EPMC9622952 | biostudies-literature
TranscriptomicsThe protective effect of edaravone on TDP-43 plus oxidative stress-induced neurotoxicity in neuronal cells: Analysis of its neuroprotective mechanisms using RNA sequencing
Edaravone is a free-radical scavenger drug that was recently approved for the treatment of amyo-trophic lateral sclerosis (ALS), a neurodegenerative disease. A pathological hallmark of ALS is the accumulation of ubiquitinated or phosphorylated aggregates of the 43-kDa transactive response DNA bindin...
ORGANISM(S): Rattus norvegicus 
2022-07-11 | GSE207578 | GEO
UnknownEdaravone alleviates Alzheimer's disease-type pathologies and cognitive deficits.
Not available
S-EPMC4413288 | biostudies-literature
UnknownEdaravone Modulates Neuronal GPX4/ACSL4/5-LOX to Promote Recovery After Spinal Cord Injury.
Not available
S-EPMC9318422 | biostudies-literature
UnknownSafety and efficacy of Edaravone Dexborneol versus edaravone for patients with acute ischaemic stroke: a phase II, multicentre, randomised, double-blind, multiple-dose, active-controlled clinical trial.
Not available
S-EPMC6812637 | biostudies-literature
UnknownIntravenous edaravone treatment in ALS and survival: An exploratory, retrospective, administrative claims analysis.
Not available
S-EPMC9358426 | biostudies-literature
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