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Oncogenic EZH2 is overexpressed and extensively involved in the pathophysiology of different cancers including extranodal natural killer/T-cell lymphoma (NKTL). However, the mechanisms regarding EZH2 upregulation is poorly understood, and it still remains untargetable in NKTL. In this study, we exam...
ORGANISM(S): Homo sapiens (Human) 
2019-08-26 | PXD015008 | Pride
Gene expression profiling was performed with total RNAs of guieranone A treated cells at IC50 concentration for 72 hours and non treated reference cells. The human leukemia cell line CCRF-CEM was used for the experiments.
ORGANISM(S): Homo sapiens 
Poly(A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail function. Here we describe poly(A)-tail length profiling by sequencing (PAL-seq) and apply it to measu...
ORGANISM(S): Arabidopsis thaliana 
Urbs1 of Ustilago maydis is a transcription factor that has been shown to repress its target genes (e.g. sid1, sid2) in the presence of iron. To identify additional genes regulated by Urbs1, we compared transcriptional profiles of the Ustilago maydis wild type strain FB1 grown in complete medium con...
ORGANISM(S): Ustilago maydis 
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