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TranscriptomicsCross-platform toxicogenomics for the prediction of nongenotoxic hepatocarcinogenesis in rat
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2014-08-18 | E-GEOD-53085 | biostudies-arrayexpress
TranscriptomicsExpression data from CD-1 mouse liver samples obtained from in-vivo treatment with genotoxic carcinogens, non-genotoxic carcinogens or non-hepatocarcinogens.
Assessing the carcinogenic potential of drug candidates is a costly procedure which requires the life-long treatment of rodents at different dose levels. A promising approach, which may to a certain degree reduce the need for animal studies in the future is toxicogenomics. The idea is to employ micr...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-44783 | biostudies-arrayexpress
TranscriptomicsCross-platform toxicogenomics for the prediction of nongenotoxic hepatocarcinogenesis in rat (miRNA)
In this study we performed microarray-based molecular profiling of liver samples from Wistar rats exposed to genotoxic carcinogens (GC), nongenotoxic carcinogens (NGC) or non-hepatocarcinogens (NC) for up to 14 days. In contrast to previous toxicogenomics studies aimed at the inference of molecular ...
ORGANISM(S): Rattus norvegicus 
2014-08-18 | E-GEOD-53083 | biostudies-arrayexpress
TranscriptomicsCross-platform toxicogenomics for the prediction of nongenotoxic hepatocarcinogenesis in rat (mRNA)
In this study we performed microarray-based molecular profiling of liver samples from Wistar rats exposed to genotoxic carcinogens (GC), nongenotoxic carcinogens (NGC) or non-hepatocarcinogens (NC) for up to 14 days. In contrast to previous toxicogenomics studies aimed at the inference of molecular ...
ORGANISM(S): Rattus norvegicus 
2014-08-18 | E-GEOD-53082 | biostudies-arrayexpress
ProteomicsCross-platform toxicogenomics for the prediction of nongenotoxic hepatocarcinogenesis in rat (protein)
In this study we performed microarray-based molecular profiling of liver samples from Wistar rats exposed to genotoxic carcinogens (GC), nongenotoxic carcinogens (NGC) or non-hepatocarcinogens (NC) for up to 14 days. In contrast to previous toxicogenomics studies aimed at the inference of molecular ...
ORGANISM(S): Rattus norvegicus 
2014-08-18 | E-GEOD-53084 | biostudies-arrayexpress
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